No Priors: Artificial Intelligence | Technology | Startups
The Best of 2025 (So Far) with Sarah Guo and Elad Gil
At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world's leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to show@no-priors.com.
Sarah Guo is a startup investor and the founder of Conviction, an investment firm purpose-built to serve intelligent software, or "Software 3.0" companies. She spent nearly a decade incubating and investing at venture firm Greylock Partners.
Elad Gil is a serial entrepreneur and a startup investor. He was co-founder of Color Health, Mixer Labs (which was acquired by Twitter). He has invested in over 40 companies now worth $1B or more each, and is also author of the High Growth Handbook.
Show Notes
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2025 has thus far been a year of great leaps and advances in AI technology. And Sarah and Elad have spoken with some of the most enterprising founders and scientific minds in the field of AI today. So we’re revisiting a few of our favorite conversations on No Priors so far in 2025 – Winston Weinberg (Harvey), Dr. Fei-Fei Li (World Labs), Brendan Foody (Mercor), Dan Hendrycks (Center for AI Safety), Noubar Afeyan (Flagship Pioneering), Brandon McKinzie and Eric Mitchell (OpenAI o3), Isa Fulford (OpenAI), Arvind Jain (Glen), and Dr. Shiv Rao (Abridge).
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Chapters:
– Episode Introduction
– Winston Weinberg on Leaning into New Capabilities
– Dr. Fei-Fei Li on Spatial Intelligence
– Brendan Foody on AI Disruption in the Workforce
– Dan Hendrycks on the Geopolitics of Superintelligence
– Noubar Afeyan on Entrepreneurship
– Brandon McKinzie and Eric Mitchell on Reasoning Models
– Isa Fulford on Training Deep Research
– Arvind Jain on Innovating Enterprise Search
– Dr. Shiv Rao on AI’s Human Impact
– Conclusion
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